Blood Bank Products

COMPONENT SHELF-LIFE STORAGE TEMPERATURE QUALITY CONTROL VOLUME INDICATIONS FOR USE CONTENT DOSAGE TRANSFUSION CRITERIA
ISG 3 yr IM
1 yr IV		 Varies Prophylaxis
Immunodeficiency
Hypogammaglob-
ulinemia		 Gamma globulins
IgG, IgM, IgA		 IM or IV
Dextran 6% (dex 40)
10% (dex 70)		 Volume expansion
burns
HES 0.06 Volume expansion
burns
Frozen RBCs 10 years  -65°C, less than Rare phenotypes RBC
Glycerol
FFP (fresh frozen plasma) 1 yr
7 yr		 -18°C
-65°C		 deficiency 200-250 mL Coagulation
deficiency
Liver disease
DIC
Massive trx		 Vs 𝛼Jk3 20-24°C
PF24 1 yr
7 yr		 -18°C
-65°C		 RhNull 150-250 mL Antigen organ nLabile factors Antigen organ Antigen organ
Cryoprecipitate Frozen: 1 yr
Thawed: 6 hr
Pooled: 4 hr		 -18°C
20-24°C		 FVIII:C 80 IU 10-25 mL Hemophilia A
VWD FXIII
deficiency
Fibrin sealant
Hypofibrinogene-
mia		 FVIII:C (80-120U)
VWF (40-70%)
FXIII (20-30%)
Fibrinogen
(150 mg/dL)		 lFibrinogen
5-10 mg/dL		 ABO
FVIII concentrates Check vial 1-6°C 10-30 mL Hemophilia A FVIII
Trace other
clotting factors		 1U FVIII/kg body wt
l 2%		 Reconstitute before
infusion
Whole blood CPD-21 d CPDA-1
35 d
CP2D-21 d
ACD-21 d		 1-6°C Hct approx. 40% 450-500 mL Volume expansion,
lO2		 RBC
Plasma
Platelets
WBCs		 l hgb 1g/dL
l hct 3%		 RBC deglycerolized
Whole blood irradiated 1-6°C 200-250 mL 450-500 mL Prevent GVHD
volume expan-
sion l O2		 RBC
Plasma
Platelets		 l hgb 1 g/dL
l hct 3%		 RBC deglycerolized
RBCs CPD-21 d CPDA-1
35 d
CP2D-21 d
ACD-21 d
AS-42 d		 1-6°C Adsorption 250-300 mL lO2 RBC l hgb 1 g/dL
l hct 3%		 RBC deglycerolized
RBC aliquots CPDA-1 35 d
(closed system)		 1-6°C Adsorption varies lO2 RBC varies RBC deglycerolized
RBC irradiated 1-6°C 200-250 mL 250-300 mL AIT/AHG RBC l hgb 1 g/dL
l hct 3%		 RBC deglycerolized
RBC leukoreduced Closed system:
same
Open system:
24 hours		 1-6°C < 5 × 106
WBCs r 85%
RBC recovery		 250-300 mL Febrile rxn, l O2 RBC
Few platelets;
residual plasma		 l hgb 1 g/dL
l hct 3%		 ABO, Rh
Washed RBCs 24 hours 1-6°C Hct 70-80% 180 mL IgA-negative
persons PNH		 RBC
WBC < 5 × 108		 l hgb 1 g/dL
l 3%		 ABO, Rh
RBC deglycerolized 24 hr 1-6°C 80% RBC recovery
< 1% glycerol
< 300 mg hgb		 180 mL Rare phenotypes
lO2		 Type 1 chain l hgb 1 g/dL
l hct 3%		 RBC deglycerolized
FIX concentrates 1-6°C 20-30 mL Hemophilia B FIX
Trace other
clotting factors		 1U FIX/kg body wt
l 1.5%		 Whole blood irradiated
RhIg 2 yr 1-6°C 1 mL Rh HDN Anti-D IgG 300 Mg
120 Mg
50 Mg		 Mother Rh-
negative; baby
Rh-positive,
Rh-unknown
NSA (normal serum albumin) 5 yr, 25% 2-10°C 50 mL
250 mL		 Plasma volume
expansion		 96% albumin 4%
globulin
PPF (plasma protein fraction, 5% 5 yr 2-10°C 250 mL Plasma volume
expansion		 Albumin 80-85%
Globulin 15-20%
Platelets, SD 5 d 20-24°C r 3 × 1011
pH r 6.2		 200-400 mL Platelet
refratoriness		 Platelets l30k-60k/ML HLA compatible
Platelets, RD other bacteria/ticks 20-24°C CE 50-70 mL Thrombocytopenia
DIC, bleeding		 Platelets, contain residual amounts of RBC l5k-10k/ML
Platelets, irradiated 20-24°C 200-250 mL Antigen organ Prevent GVHD Platelets Antigen organ Antigen organ
Platelets, pooled 20-24°C RBC
Plasma
Platelets		 Epitopes/Antigens Thrombocytopenia
DIC, bleeding		 Platelets Epitopes/Antigens
Platelets, leukoreduced 20-24°C < 5 × 106 SD
< 8.3 × 105 RD		 𝛼i Febrile rxns Platelets RD: l 5-10k
SD: l 30-60k		 Direct antigen
Granulocytes 24 hr 20-24°C RhNull 200-600 mL G & D, or G & C WBC
RBC
Plts plasma		 RhAG ABO, Rh, HLA
Granulocytes, irradiated 24 hr 20-24°C RhNull 200-600 mL -65°C Antigen organ Antigen organ Antigen organ
SDP 1-6°C liquid 5 days after WB
expiration
Frozen: 5 yr		 Frozen 6 hr 150-250 mL Stabile clotting
factors		 Same Same